Issue 11 of The NZ Journal of Natural Medicine features an article by Dr Martha Herbert, PhD, MD.  Dr Herbert is an assistant professor of Neurology at Harvard Medical School and works as a paediatric neurologist at Massachusetts General Hospital in Boston.

Dr Herbert’s article “Is EMR another cause of autism?” summarises the evidence of how exposure to electromagnetic radiation may be contributing to the large increase in the numbers of children developing this distressing condition.  More information about Dr Herbert and her work may be found at::  http://nmr.mgh.harvard.edu/transcend/ and www.marthaherbert.org

 

Due to the large number of references for Dr Herbert’s article, they have been posted on this website, rather than being printed in issue 11.  References for her article are below:

 

References

 

1.            Herbert M. Time to Get a Grip. Autism Advocate 2006;45:19-26  http://www.autism-society.org/site/DocServer/eh_get_a_grip.pdf?docID=4821.

2.            Milham S. Dirty Electricity: Electrification and the Diseases of Civilization: iuniverse.com; 2010.

3.            Rapin I, Katzman R. Neurobiology of autism. Ann Neurol 1998;43:7-14.

4.            Herbert MR, Sage C. Autism and EMF? Plausibility of a Pathophysiological Link, Parts I and II. Pathophysiology In press.

5.            Hertz-Picciotto I, Delwiche L. The rise in autism and the role of age at diagnosis. Epidemiology 2009;20:84-90.

6.            King M, Bearman P. Diagnostic change and the increased prevalence of autism. Int J Epidemiol 2009;38:1224-34.

7.            Grether JK, Rosen NJ, Smith KS, Croen LA. Investigation of shifts in autism reporting in the California Department of Developmental Services. J Autism Dev Disord 2009;39:1412-9.

8.            Herbert MR, Weintraub K. The Autism Revolution: Whole Body Strategies for Making Life All It Can Be. New York, NY: Random House with Harvard Health Publications; 2012.

9.            Autism WHY and HOW. 2012. at www.autismWHYandHOW.org.)

10.          Herbert MR. Autism: The centrality of active pathophysiology and the shift from static to chronic dynamic encephalopathy: Taylor & Francis / CRC Press; 2009.

11.          Herbert M. Autism: From Static Genetic Brain Defect to Dynamic Gene‐Environment Modulated Pathophysiology. In: Krimsky S, Gruber J, eds. Genetic Explanations: Sense and Nonsense. Cambridge, MA: Harvard University Press; 2013:122-46.

12.          Herbert MR. Contributions of the environment and environmentally vulnerable physiology to autism spectrum disorders. Curr Opin Neurol 2010;23:103-10.

13.          Just MA, Cherkassky VL, Keller TA, Minshew NJ. Cortical activation and synchronization during sentence comprehension in high-functioning autism: evidence of underconnectivity. Brain 2004;127:1811-21.

14.          Muller RA, Shih P, Keehn B, Deyoe JR, Leyden KM, Shukla DK. Underconnected, but how? A survey of functional connectivity MRI studies in autism spectrum disorders. Cereb Cortex 2011;21:2233-43.

15.          Wass S. Distortions and disconnections: disrupted brain connectivity in autism. Brain Cogn 2011;75:18-28.

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17.          Lobikin M, Chernet B, Lobo D, Levin M. Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo. Phys Biol 2012;epub:epub.

18.          Herbert MR, Sage C. Findings in Autism Spectrum Disorders consistent with Electromagnetic Frequencies (EMF) and Radiofrequency Radiation (RFR). In: Sage C, Carpenter DO, eds. BioInitiative Update: www.BioInitiative.org; 2012.

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38.          Palmieri L, Persico AM. Mitochondrial dysfunction in autism spectrum disorders: cause or effect? Biochim Biophys Acta 2010;1797:1130-7.

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40.          Pessah IN, Lein PJ. Evidence for Environmental Susceptibility in Autism: What We Need to Know About Gene x Environment Interactions: Humana; 2008.

41.          Stamou M, Streifel KM, Goines PE, Lein PJ. Neuronal connectivity as a convergent target of gene-environment interactions that confer risk for Autism Spectrum Disorders. Neurotoxicol Teratol 2012.

42.          Bachmann M, Lass J, Kalda J, et al. Integration of differences in EEG analysis reveals changes in human EEG caused by microwave. Conf Proc IEEE Eng Med Biol Soc 2006;1:1597-600.

43.          Marino AA, Nilsen E, Frilot C. Nonlinear changes in brain electrical activity due to cell phone radiation. Bioelectromagnetics 2003;24:339-46.

44.          Marino AA, Carrubba S. The effects of mobile-phone electromagnetic fields on brain electrical activity: a critical analysis of the literature. Electromagn Biol Med 2009;28:250-74.

45.          Vecchio F, Babiloni C, Ferreri F, et al. Mobile phone emission modulates interhemispheric functional coupling of EEG alpha rhythms. Eur J Neurosci 2007;25:1908-13.

46.          Hountala CD, Maganioti AE, Papageorgiou CC, et al. The spectral power coherence of the EEG under different EMF conditions. Neurosci Lett 2008;441:188-92.

47.          Duffy FH, Als H. A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls – a large case control study. BMC Med 2012;10:64.

48.          Isler JR, Martien KM, Grieve PG, Stark RI, Herbert MR. Reduced functional connectivity in visual evoked potentials in children with autism spectrum disorder. Clin Neurophysiol 2010.

49.          Murias M, Swanson JM, Srinivasan R. Functional connectivity of frontal cortex in healthy and ADHD children reflected in EEG coherence. Cereb Cortex 2007;17:1788-99.

50.          Murias M, Webb SJ, Greenson J, Dawson G. Resting state cortical connectivity reflected in EEG coherence in individuals with autism. Biol Psychiatry 2007;62:270-3.

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52.          Rossignol DA, Frye RE. Melatonin in autism spectrum disorders: a systematic review and meta-analysis. Dev Med Child Neurol 2011;53:783-92.

53.          Buckley AW, Rodriguez AJ, Jennison K, et al. Rapid eye movement sleep percentage in children with autism compared with children with developmental delay and typical development. Arch Pediatr Adolesc Med 2010;164:1032-7.

54.          Giannotti F, Cortesi F, Cerquiglini A, Vagnoni C, Valente D. Sleep in children with autism with and without autistic regression. J Sleep Res 2011;20:338-47.

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57.          Bilbo SD, Jones JP, Parker W. Is autism a member of a family of diseases resulting from genetic/cultural mismatches? Implications for treatment and prevention. Autism Res Treat 2012;2012:910946.

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63.          Szmigielski S, Bortkiewicz A, Gadzicka E, Zmyslony M, Kubacki R. Alteration of diurnal rhythms of blood pressure and heart rate to workers exposed to radiofrequency electromagnetic fields. Blood Press Monit 1998;3:323-30.

64.          Bortkiewicz A, Gadzicka E, Zmyslony M, Szymczak W. Neurovegetative disturbances in workers exposed to 50 Hz electromagnetic fields. Int J Occup Med Environ Health 2006;19:53-60.

65.          Graham C, Cook MR, Sastre A, Gerkovich MM, Kavet R. Cardiac autonomic control mechanisms in power-frequency magnetic fields: a multistudy analysis. Environ Health Perspect 2000;108:737-42.

66.          Saunders RD, Jefferys JG. A neurobiological basis for ELF guidelines. Health Phys 2007;92:596-603.

67.          Buchner K, Eger H. Changes of Clinically Important Neurotransmitters under the Influence of Modulated RF Fields—A Long-term Study under Real-life Conditions (translated; original study in German). Umwelt-Medizin-Gesellschaft 2011;24:44-57.

68.          Bellieni CV, Acampa M, Maffei M, et al. Electromagnetic fields produced by incubators influence heart rate variability in newborns. Arch Dis Child Fetal Neonatal Ed 2008;93:F298-301.

69.          Narayanan A, White CA, Saklayen S, et al. Effect of propranolol on functional connectivity in autism spectrum disorder–a pilot study. Brain Imaging Behav 2010;4:189-97.

70.          Anderson CJ, Colombo J. Larger tonic pupil size in young children with autism spectrum disorder. Dev Psychobiol 2009;51:207-11.

71.          Anderson CJ, Colombo J, Unruh KE. Pupil and salivary indicators of autonomic dysfunction in autism spectrum disorder. Dev Psychobiol 2012.

72.          Daluwatte C, Miles JH, Christ SE, Beversdorf DQ, Takahashi TN, Yao G. Atypical Pupillary Light Reflex and Heart Rate Variability in Children with Autism Spectrum Disorder. J Autism Dev Disord 2012.

73.          Ming X, Bain JM, Smith D, Brimacombe M, Gold von-Simson G, Axelrod FB. Assessing autonomic dysfunction symptoms in children: a pilot study. J Child Neurol 2011;26:420-7.

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75.          Toichi M, Kamio Y. Paradoxical autonomic response to mental tasks in autism. J Autism Dev Disord 2003;33:417-26.

76.          Ming X, Julu PO, Brimacombe M, Connor S, Daniels ML. Reduced cardiac parasympathetic activity in children with autism. Brain Dev 2005;27:509-16.

77.          Mathewson KJ, Drmic IE, Jetha MK, et al. Behavioral and cardiac responses to emotional stroop in adults with autism spectrum disorders: influence of medication. Autism Res 2011;4:98-108.

78.          Cheshire WP. Highlights in clinical autonomic neuroscience: New insights into autonomic dysfunction in autism. Auton Neurosci 2012;171:4-7.

79.          Chang MC, Parham LD, Blanche EI, et al. Autonomic and behavioral responses of children with autism to auditory stimuli. Am J Occup Ther 2012;66:567-76.

80.          Kesari KK, Kumar S, Behari J. 900-MHz microwave radiation promotes oxidation in rat brain. Electromagn Biol Med 2011;30:219-34.

81.          Oktem F, Ozguner F, Mollaoglu H, Koyu A, Uz E. Oxidative damage in the kidney induced by 900-MHz-emitted mobile phone: protection by melatonin. Arch Med Res 2005;36:350-5.

82.          Lai H, Singh NP. Melatonin and a spin-trap compound block radiofrequency electromagnetic radiation-induced DNA strand breaks in rat brain cells. Bioelectromagnetics 1997;18:446-54.

83.          Xu S, Zhou Z, Zhang L, et al. Exposure to 1800 MHz radiofrequency radiation induces oxidative damage to mitochondrial DNA in primary cultured neurons. Brain Res 2010;1311:189-96.

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85.          Bellieni CV, Tei M, Iacoponi F, et al. Is newborn melatonin production influenced by magnetic fields produced by incubators? Early Hum Dev 2012;88:707-10.

86.          Bellieni CV, Pinto I, Bogi A, Zoppetti N, Andreuccetti D, Buonocore G. Exposure to electromagnetic fields from laptop use of “laptop” computers. Arch Environ Occup Health 2012;67:31-6.

87.          Agarwal A, Deepinder F, Sharma RK, Ranga G, Li J. Effect of cell phone usage on semen analysis in men attending infertility clinic: an observational study. Fertil Steril 2008;89:124-8.

88.          Agarwal A, Desai NR, Makker K, et al. Effects of radiofrequency electromagnetic waves (RF-EMW) from cellular phones on human ejaculated semen: an in vitro pilot study. Fertil Steril 2009;92:1318-25.

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